Abstract
Transcranial magnetic stimulation (TMS) can be interleaved with functional magnetic resonance imaging (fMRI) to visualize regional brain activity in response to direct, non-invasive, TMS stimulation. It is a promising tool for studying brain function. This chapter provides an overview of the methodology and some of the recent work. Issues involved in performing interleaved fMRI and repetitive TMS include safety, the problems with static and dynamic artifacts, the problem of radiofrequency interference, and the requirements for minimizing the interaction between the TMS pulse and MR image acquisition. A major practical difficulty is the accurate positioning of the TMS coil within the MRI scanner for stimulating a particular area of an individual's brain cortical anatomy, especially when there is no overt response associated with that area.
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