Abstract
Inorganic nanoparticles are currently under extensive exploration for their potential use in topical and transdermal drug delivery. Compared with organic nanoparticles, they offer higher chemical and mechanical stability and easier surface functionalization, and they possess a tunable particle size and varied morphology. This chapter summarizes the design criteria of inorganic nanoparticles for transdermal and/or topical applications, and some of the intriguing examples have been discussed in detail along with existing challenges and future perspectives.
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