Abstract
Chitosan is well-known as an abundant natural polymeric biomaterial. It is produced from chitin by hydrolytic deacetylation. Because of its appealing biomedical properties, such as biodegradability, biocompatibility, nontoxicity, chemical versatility, gel- and film-forming ability, high adsorption capacity, and polyelectrolyte properties, chitosan has been considered a suitable biopolymeric excipient material for fabricating several delivery devices for drugs, gene, proteins and peptides, growth factors, and so forth. In addition, chitosan-based nanocomposites have been extensively applied in tissue engineering. Chitosan-based nanocomposite films, hydrogels, and sponges have been widely used in the field of wound management owing to their antimicrobial properties. Chitosan-based nanocomposites also have applications in bioimaging. This chapter briefly describes the source, structure, and properties of chitosan and describes in depth the applications of chitosan-based nanocomposites in the various fields of biomedical research.
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