Abstract
The personalized medicine movement pivots on the integration of patients’ genetic and genomic data for prevention, diagnosis, and treatment. However, it does not refer to a single test or type of data like a gene sequence, but rather assessment of a range of molecular-based changes that are impacted by and can impact the macro- and micro-environment. At this point in time, several areas of research are actively under investigation, yielding new clues about human health and disease, and informing development of new clinical interventions. These areas of research and clinical applications also raise a host of issues that will need to be addressed to enable the continued pace of research and clinical implementation. This chapter aims to provide an overview of several areas of research that are driving the personalized medicine movement as well as some of the ethical, legal, and clinical issues that have been raised.
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