Abstract
Gamma-hydroxybutyric acid (GHB) is a central nervous system depressant. It has been widely known as a date rape drug used in instances of drink spiking leading to drug-facilitated sexual assault. Common methods of GHB detection are based on laboratory equipment and require multiple steps. They can only be used to detect GHB in forensic samples of presumed victims, while cannot be routinely applied for multiple sample field analysis. Recently, several optical sensors for GHB have been developed by research groups and companies. They exhibit great potential in efficient and convenient detection for field test of GHB. In this chapter, we will summarize available GHB optical assay sensors. Especially, we will discuss in detail how these sensors were developed and how they detect GHB in drink samples. We hope this discussion will draw more research attention to GHB detection and help to solve the problem of drug-facilitated sexual assault.
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