Abstract
The outburst of nanotechnology has facilitated a substantial upsurge in the prolific utilization of nanoparticles in biomedical applications. The area of drug delivery has been tremendously benefitted by developing a plethora of nanostructured systems for the effective transport and controlled release of therapeutic molecules at the target site. However, the wide arena of gastrointestinal tract conferred a high level of complexity in terms of its varied physiological and morphological parameters for effective drug-delivery regimes. Thus nanomediated targeted drug delivery holds promising potential in overcoming various conventional barriers of drug delivery in the gastrointestinal tract and leads to the paradigmatic shift in the treatment of various gastrointestinal disorders. Therefore this chapter delineates various types of nanostructures used as drug-delivery vehicles in various gastrointestinal disorders simultaneously emphasized technological bottlenecks and future research priorities in the development of commercialized nanovehicles for drug-delivery applications.
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