Chapter 32 - Transcutaneous oxygen and carbon dioxide monitoring in sick neonates using a single combined sensor

Abstract

This chapter describes a study to examine the transcutaneous oxygen and carbon dioxide monitoring in sick neonates using a single combined sensor. Critically ill neonates requiring ventilatory support and umbilical artery catheterization were selected for the study. The Biochem combined transducer was used throughout the study period. Pearson's linear regression analysis was used for correlation of transcutaneous values to arterial values. The combined sensor was used in 11 critically ill neonates during the first phase. Their clinical data and the correlation of arterial oxygen and carbon dioxide tension with the transcutaneous values are shown. A total of 101 oxygen and 95 carbon dioxide values were available for analysis. Transcutaneous PO 2 and PCO 2 correlated well with the arterial values, even though tcPO 2 values were lower than arterial values. Due to the significant differences between transcutaneous values and arterial values, the transducer was modified as described above. During the second phase, a total of 24 neonates were studied. In cases with poor peripheral perfusion, the transcutaneous O 2 was lower and tcPCO 2 was significantly higher than arterial values. In addition, four infants were hyperventilated as a part of the management of persistent fetal circulation.