Abstract
Microfluidics and microfluidic devices are the perfect platform to perform cell-, tissue-, and organ-based studies. Not only is microfluidics at the same scale as most cells and organ features but also most microfluidic physical phenomena (e.g., laminar flow, high surface to volume ratio) are closer to what is physiologically experienced by cells than with standard equipment. Microfluidics also offers other advantages: (1) the flow and level of oxygen are physiologically relevant, (2) biocompatible materials, (3) 2D/3D fabrication and assembly for 2D/3D cell culture, (4) diverse geometries and operation modes, (5) high customization of surface features, (6) compatibility with standard analytical methods, and (7) available miniaturized analytical sensors.
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