Abstract

A significant portion of the world population has been affected by bone diseases like osteoporosis and bone cancer. A site-specific drug delivery approach can result in safe and effective clinical outcomes in the treatment of these diseases. In this context, the delivery of therapeutic agents using magnetic nanoparticles (MNPs) has been widely investigated over the past few decades. MNPs have attractive properties such as superparamagnetism, which has led to them being widely recognized as a promising tool in biomedical applications, including protein or cell separation, magnetic resonance imaging, and cancer hyperthermia treatment, besides being used as drug delivery vehicles and signal enhancement agents. In addition to the size of MNPs, surface functionalization and coatings are critical parameters that need to be considered for site-specific targeting. In this chapter, we cover the synthesis of magnetic nanoparticles (magnetite and maghemite), their functionalization, characterization, and applications in treating bone diseases.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.