Abstract
Pain originating from the manubriosternal joint can mimic pain of cardiac origin. The manubriosternal joint is susceptible to the development of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, Reiter syndrome, and psoriatic arthritis. The joint can also be traumatized during acceleration-deceleration injuries and blunt trauma to the chest. With severe trauma, the joint may subluxate or dislocate. Overuse or misuse can result in acute inflammation of the manubriosternal joint, which can be quite debilitating. The joint is also subject to invasion by tumor from primary malignant tumors, including thymoma, or from metastatic disease. Rarely, septic arthritis of the manubriosternal joint can occur.
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