Abstract
The application of nanotechnology in medicine represents a great opportunity to enhance the effectiveness of currently available medical treatments, especially focused on challenging healthcare issues, such as skin wound regeneration. Hence, in the last few decades, nanobiomaterials have been extensively studied and optimized for the development of nanoscale drug-delivery systems releasing drugs, such as growth factors, cytokines, or antimicrobials, for skin wound repair. In this regard, several natural or synthetic materials have been studied due to their similarities to the skin and biocompatible properties, or due to their antibacterial or antiseptic effect. In addition, materials can also be engineered as scaffolds for the development of novel wound dressings. Thus, this chapter presents an overview of the current nanotechnological approaches used for the controlled release of drugs in the field of skin wound regeneration, particularly emphasizing polymeric and lipid nanoparticles (NPs), silver NPs, nanofibrous structures, nanosheets, and nanohybrids.
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