Abstract
Brain metastases are the most common type of brain tumors with an incidence of 2.8 to 14.3 individuals per 100000 population. In addition, brain metastases represent 9% to 17% of systemic cancers. The most common brain metastases are due to lung cancer, breast cancer, melanoma, renal cell cancer and colorectal cancer. The age-specific incidence depends on the primary tumor. Children have a different brain metastases profile from adults: the most common metastatic cancers in children are germ cell tumors, sarcoma and neuroblastoma. Brain metastases are associated with poor prognosis, which impacts both the length and the quality of life. Without treatment, the patients die within a few months after the diagnosis of brain metastases. Functionally, the patients become impaired – they are devastated by seizures, weakness or paralysis, language deficits, and have sharp cognitive decline. In addition to the negative effects on the quality of life, the financial burden associated with the care and treatment of these patients is very high. Early detection of brain metastases in cancer patients is the key to minimizing complications and extending the quality and the quantity of life of these patients.
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