Abstract

Diabetic polyneuropathy (DPN) has several forms of clinical presentation. It may be asymptomatic, or present with prominent sensory symptoms, including neuropathic pain. Clinical neurologic examination is helpful in identifying patients with distal sensory deficits, loss of deep tendon reflexes, early distal motor abnormalities and skin ulceration. Other causes of polyneuropathy are important to exclude. For serial evaluations and research purposes, several clinical severity grading scales have been developed.

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