Abstract

This chapter reviews several animal models of social stress with a focus on those involving social hierarchy. The chapter describes an appreciation of the different types of laboratory animal models available for social stress research. Manipulations of an animal's environment or the animal itself to elicit a desired response may, appear to be an appropriate model of a human disease condition. However, there are many other aspects of the manipulation that must be addressed such as the ethological relevance of the stressor itself, the influence of the type of interactions that are allowed to occur between animals, and the appropriateness of the included control groups for comparison. It is clear that animal models of social stress have facilitated research in numerous areas of basic and clinical science and will continue to do so as long as the model is recognized and respected for its strengths as well as its limitations.

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