Abstract
Biocompatible and biodegradable nanoparticles (NPs) have received significant interest in recent years as suitable carriers of or site specific delivery of therapeutics to overcome communicable and non-communicable injury-based disorders. Carbohydrate-based natural polymers have gained much attention as drug delivery systems (DDSs) due to their eco-friendly nature, cost effectiveness, enhanced biocompatibility, superior encapsulation, and convenient release of drugs. Among the natural polymers, starch as the most abundant renewable polymer is widely considered as a promising candidate for drug delivery and biomedical applications as binder, filler, and disintegrant due to its superior loading efficiency (via certain immobilization strategies) and controlled release of the drugs, therapeutics, enzymes, ayurvedic compounds, and other kinds of bioactive compounds to the targeted site. Functionalization and surface modification of starch by physical, chemical, and enzymatic methods improves the pharmaceutical application of starch as DDS, implants, stent, transdermal and opthalmic systems. This chapter integrates the fabrication, processing, and characterization of starch nanoparticles as micro- and nano-based DDSs and its application in the treatment of cancer, neurodegenerative disorders, and infectious disorders. The content, figures, and tables of this review consolidate the various approaches and their mechanism involved in the fabrication of starch-based DDS in order to achieve the pharmaceutical and biomedical applications.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
