Abstract

Nutrition research has undergone revolutionary changes with a move away from a focus on single nutrients to an assessment of overall dietary intake. Furthermore, there has been a realization that not everyone responds in the same way to dietary interventions and the concept of personalized or precision nutrition has emerged. Underpinning these and other changes in nutrition research has been the increased application of nutrigenomics techniques and in particular metabolic phenotyping. Metabolic phenotyping in nutrition research has been particularly successful in three areas: (1) Studying differential responses to dietary intervention studies (2) Personalized nutrition and (3) Assessment of dietary intake and in particular dietary patterns. Examples from each of these three areas will be presented and an overview of the keys steps needed to ensure that we get the maximal potential from metabolic phenotyping in nutrition research.

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