Abstract
Widespread human exposure to known or suspected endocrine-disrupting chemicals (EDCs) has been documented worldwide, while rates of endocrine-related diseases and disorders among children are increasing. This chapter provides an overview of the current state of the epidemiological evidence for the adverse impacts of common persistent and nonpersistent EDCs on child development. The selected health end points discussed here include fetal growth, early reproductive tract development, pubertal development, obesity, and neurodevelopment. Despite their limitations, the studies mentioned here add to a growing body of evidence that exposure to chemicals commonly found in consumer goods, personal care products, food, drinking water, and other sources may adversely affect child development through altered endocrine function in a variety of pathways. Given the range of these potential serious developmental effects, efforts to reduce EDC exposure as a precaution among pregnant women and children are warranted.
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