Abstract

It is important to understand the differential diagnosis for solid and cystic liver lesions. Malignant solid liver lesions include metastases, lymphoma, and primary malignancies such as hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC). Benign solid liver lesions are most commonly hemangiomas, focal nodular hyperplasia, or adenomas. Malignant cystic liver lesions include metastases, HCC, CC, and biliary cystadenocarcinomas. For benign cystic liver lesions, consider cysts, infections (pyogenic, amoebic, echinococcal), biliary hamartomas (von Myenberg complexes), and biliary cystadenomas. An FDG-avid liver lesion is suspicious for malignancy unless proven otherwise by anatomic imaging or pathology.

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