Abstract

Telomeres are the noncoding regions of repetitive nucleotide sequences at the end of chromosomes. The length of a telomere may act as a biological clock. The study of telomeres is of growing interest in precision nutrition, since they are not only related to the aging process but there is also evidence that telomere attrition is associated with oxidative stress, inflammation, and environmental factors. This process, triggered by genetic and external factors such as alcohol abuse, smoking, consumption of fast food, or a sedentary lifestyle, leads to premature cell senescence. It has been shown that a healthy lifestyle and an antioxidant-rich food intake could contribute to delay age-related diseases by keeping telomere integrity. In this chapter, the role of antioxidant nutrients on telomere length is carefully reviewed in the framework of precision nutrition.

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