Abstract
Skin diseases in humans are common and can cause complications if not treated properly. A number of antifungal drugs are exploited for the treatment of fungal skin infections, but most of the pathogenic fungi, especially yeasts, can develop resistance towards antifungal drugs. Adverse effects of topical and systemic antifungal drugs can sometimes also limit their use. Nanoparticles offer a lower risk of systemic side effects for the treatment of skin infections. Nanoparticles such as silver, copper, gold, sulfur, titanium dioxide, zinc oxide, and some others have been employed for the management of skin disorders such as skin candidiasis, pityriasis versicolor, tinea, folliculitis, and seborrhoeic dermatitis. Nanoparticle-based formulations have been gaining importance due to their targeted delivery, increased skin permeability, and controlled release for the treatment of skin infections. They also offer an advantage by increasing bioavailability of active components with prolonged effect at the site of infection. The present chapter is focused on different nanoparticles and their formulations used for the treatment of various skin infections caused by fungi in humans.
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