Abstract
Publisher Summary This chapter focuses on the morphology of (bio) membrane fusion. Because detailed knowledge of sample processing is required for the correct interpretation of electron microscopic data, especially in the field of membrane fusion research, the most important EM techniques are mentioned together with some of their specific advantages and disadvantages. After defining biomembrane fusion in morphological terms, turn to the molecular models that have been proposed for membrane fusion, consider the role of fusogenic lipids in model membrane fusion, and discuss the significance of the data obtained in model membrane systems in light of the typical characteristics of biomembrane fusion. The role of specific proteins in the induction of biomembrane fusion is addressed, taking the best studied biological fusogenic protein to date, the influenza virus hemagglutinin, as a starting point.
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