Abstract
An understanding of the mechanisms and theories of electric field-assisted transport is required to utilize iontophoretic drug delivery across a biological membrane effectively. The present chapter covers the topics of electrotransport across membranes in biological media and its applications in transdermal, transscleral and transungual drug delivery. It is aimed at graduate students and scientists in pharmaceutics, engineering and biological research. Electrotransport theories are first reviewed. Membrane transport under variable electric fields and boundary conditions, such as symmetric conditions of the same total ion concentration and asymmetric conditions of different total ion concentrations across the membrane, are discussed. Electrotransport across multiple membranes during constant current iontophoresis and under alternating current are also discussed. The influences of electroosmosis and electropermeabilization in iontophoretic drug delivery are described. Transdermal, transscleral and transungual iontophoretic drug delivery is then reviewed.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
