Chapter 1 - Natural products with α-tertiary amine

Abstract

The key α-tert-alkylamino carbon center in the total synthesis of aforementioned natural products has been accessed via different synthetic methodologies including asymmetric Strecker reaction, Overman rearrangement, aldol condensation, enolate Claisen rearrangement, carbene insertion into C–H bond, Diels–Alder reaction, and many more that have been highlighted in the synthetic layout. This book elaborates the different synthetic routes that have been adopted for syntheses of natural products having α-tert-alkylamino carbon center. Moreover, the synthetic approaches to access the advance intermediates of these natural products have also been summarized.