Chapter 1 - Description of the fuzzy oil drop model

Abstract

This diagram demonstrates the core concept of the fuzzy oil drop (FOD) model, which posits the existence of an external force field generated by the aqueous solvent. The external field guides hydrophobic residues toward the center of the protein body, while hydrophilic residues are instead exposed on its surface. The process continues as the encapsulating ellipsoid capsule shrinks (via changes in σ coefficients of the 3D Gaussian). The gradual increase of gray color visualize the increase of hydrophobicity concentration.