Abstract
Epithelial ovarian cancer (EOC) is the leading cause of death among all gynecological malignancies. Due to late presentation and diagnosis at an advanced stage, the mortality rate from ovarian cancer continues to be high. A lot of research for development of specific newer biomarkers for diagnosis and prognosis in EOC is occurring at a rapid pace. EOC is a highly heterogeneous disease characterized by many diverse histological and molecular subtypes [1]. Morphologically, these tumours are typed into serous, mucinous, endometrioid, clear cell, brenner and seromucinous types. These are then further divided into benign, borderline and malignant depending on the degree of cell proliferation, nuclear atypia and presence or absence of stromal invasion [2].
Highlights
A lot of research for development of specific newer biomarkers for diagnosis and prognosis in Epithelial ovarian cancer (EOC) is occurring at a rapid pace
EOC is a highly heterogeneous disease characterized by many diverse histological and molecular subtypes [1]. These tumours are typed into serous, mucinous, endometrioid, clear cell, brenner and seromucinous types
These are further divided into benign, borderline and malignant depending on the degree of cell proliferation, nuclear atypia and presence or absence of stromal invasion [2]
Summary
Epithelial ovarian cancer (EOC) is the leading cause of death among all gynecological malignancies. Due to late presentation and diagnosis at an advanced stage, the mortality rate from ovarian cancer continues to be high.
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