Abstract
Pediatric neurosurgeons at Children’s Memorial Hospital, Chicago, review their long-term experience and the evolution of the etiology, diagnosis and management of patients born with myelomeningocele (MM) in 1975-1979 and followed for 25 years in a multi-disciplinary spina bifida clinic.
Highlights
Pediatric neurosurgeons at Children’s Memorial Hospital, Chicago, review their longterm experience and the evolution of the etiology, diagnosis and management of patients born with myelomeningocele (MM) in 1975-1979 and followed for 25 years in a multidisciplinary spina bifida clinic
Incidence was declining before use of folic acid, but following periconceptual multi-vitamin supplementation, a significant decrease occurred (MRC, 1991)
The authors comment that shunt malfunction is a primary consideration in long-term care of MM, and adult colleagues need to become familiar with this problem
Summary
Pediatric neurosurgeons at Children’s Memorial Hospital, Chicago, review their longterm experience and the evolution of the etiology, diagnosis and management of patients born with myelomeningocele (MM) in 1975-1979 and followed for 25 years in a multidisciplinary spina bifida clinic. Incidence was declining before use of folic acid, but following periconceptual multi-vitamin supplementation, a significant decrease occurred (MRC, 1991). Long-term outcome of non-selective treatment of 118 infants with MM born 1975-79, and followed at Children’s Memorial Hospital, compared to a cohort born in 2000-2005, found a decline in the number of live births with MM: 16-32/year in the older cohort vs 113/year in the younger cohort of 40 children.
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