Abstract
In the 110 years since its original description haemochromatosis has been variously considered to be a form of alcoholic cirrhosis, a result of diabetes and an inherited metabolic defect of iron metabolism (Figure 1). The association between cirrhosis, hepatic pigment deposits and diabetes mellitis was recognized first by Troisier M. (1871) “la cirrhose pigmentaire dans le diabete sucre”, Hanot (1886) suggested the term “bronze diabetes” for the disorder because he believed that the diabetes was of primary importance causing both the cirrhosis and skin pigmentation. It was von Recklinghausen (1889) who proposed the term haemochromatosis because he believed that the pigment came from the blood. Although strictly a misnomer this term has been used ever since to describe the syndrome of iron loading associated with tissue injury.
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