Changes of urinary symptoms after transurethral resection of the prostate and its correlation with clinical parameters

Abstract

To evaluate the changes of different urinary symptoms of benign prostatic hyperplasia (BPH) patients after transurethral resection of the prostate (TURP) and its correlation with preoperative clinical parameters. Two hundred and eighty-one BPH patients were followed-up 3 - 6 months after TURP, whose postoperative International Prostate Symptom Score (IPSS) and Quality of Life (QOL) score were compared with those of preoperation. The relationship between the symptom score changes and clinical data were analyzed. The patients aged (70 +/- 6) years, with preoperative prostate volume (75 +/- 39) ml, T-PSA (5 +/- 5) ng/ml, Qmax (8 +/- 3) ml/s, average tissue weight resected (32 +/- 19) g. Before operation, mean IPSS was 24 +/- 7, QOL 4.6 +/- 1.0, mean obstructive symptom score was 3.6 +/- 1.2, mean irritation symptom score was 3.5 +/- 1.0. After operation mean IPSS was 7 +/- 7 and QOL was 1.2 +/- 1.1, which were significantly decreased. The deduction rate of the mean obstructive symptom score was greater than that of the mean irritative symptom score. Among the 7 urinary symptoms, nocturia and frequency were the two that changed least, with postoperative score of 2.2 +/- 1.1 and 1.2 +/- 1.4 respectively. Scores of urinary symptoms and QOL of BPH patients were significantly improved after TURP. The improvements of the symptom scores and QOL are correlated to the preoperative scores. There is no correlation between symptom score improvements and patients' age, preoperative prostate volume, T-PSA, Qmax and tissue weight resected. Improvement of average obstructive symptom score is greater than that of irritative symptom score. Among the seven symptoms, nocturia is the one with lowest improvement after TURP.