Abstract
PET study of cerebral glucose metabolism was performed in 73 children with epilepsy and mental retardation. Expressive speech disorders were associated with decrease of cerebral metabolism rate of glucose (CMRglu) in the upper frontal gyrus, caudate nucleus and thalamus of the left and right hemispheres. In the group with combined expressive and impressive speech disorders the significant CMRglu reduction in the middle temporal and supramarginal gyrus of the left hemisphere was observed. The obtained results confirm that the brain structures associated with the executive functions and complex association processes have a great significance in the speech development.
Highlights
Проведено позитронно-эмиссионной томографии (ПЭТ)-исследование церебрального метаболизма глюкозы у 73 детей с эпилепсией и задержкой психического развития (ЗПР)
PET study of cerebral glucose metabolism was performed in 73 children with epilepsy and mental retardation
Expressive speech disorders were associated with decrease of cerebral metabolism rate of glucose (CMRglu) in the upper frontal gyrus, caudate nucleus and thalamus of the left and right hemispheres
Summary
Проведено ПЭТ-исследование церебрального метаболизма глюкозы у 73 детей с эпилепсией и задержкой психического развития (ЗПР). При нарушениях экспрессивной речи выявлено снижение скорости метаболизма глюкозы (СМГ) в верхней лобной извилине, хвостатом ядре и таламусе левого и правого полушарий. При сочетании нарушений экспрессивной и импрессивной речи значимое снижение СМГ наблюдалось в средней височной и надкраевой извилине левого полушария.
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