Changes of specific activity and synthesizing activity of catalase in acatalasemia mouse liver.

Abstract

The ratio of the amounts of catalase in liver supernatant of the normal to that of acatalasemia mice, determined by the immunochemical method, was 100 : 78. In turn, the ratio of the specific activities of catalase in the same samples was 100 : 31. Experimental results obtained suggested that 14C-leucine incorporating activity of liver microsomes from acatalasemia mouse in the cell-free protein bio-synthesis system was less than that from normal mouse liver microsomes. The possibility was also discussed that the enzymic activity of catalase molecules from the acatalasemia mice may be lower than that of the catalase molecules from normal mice.