Changes of separate kidney function after percutaneous renal artery stent implantation for treatment of atherosclerotic renal artery stenosis

Abstract

Objective: To investigate the clinical efficacy of percutaneous renal artery stenting (PTRAS) for the treatment of atherosclerotic renal artery stenosis (ARAS) . Methods: Totally 31 ARAS patients undergoing PTRAS in Aerospace Center Hospital from January 1, 2013 to December 31, 2015 were selected, with unilateral renal artery stenosis. All the patients were followed up for 12 months to observe the achievement ratio of PTRAS and changes of blood pressure and antihypertensive drug categories. The changes of single kidney glomerular filtration rate (SKGFR) were evaluated by renal dynamic imaging. Results: The achievement ratio was 100%, without severe complications. All patients were followed up for 3, 6 and 12 months after operation. The systolic blood pressure, diastolic blood pressure and antihypertensive drug categories were significantly lower than those before the operation, but there was no significant change in serum creatinine. The SKGFR and total GFR in stent side were significantly higher than those before operation, but there was no significant change in non stent side SKGFR after operation. The patients were divided into two groups according to the preoperative SKGFR value in stent side of 20 ml/min, SKGFR<20 ml/min group (16 cases) and SKGFR≥20 ml/min group (15 cases) , and the changes of SKGFR before and after operation were analyzed in two groups. Conclusions: PTRAS has high achievement ratio and low complication rate in the treatment of ARAS. The separate kidney function of the stent side is significantly improved, the smaller the SKGFR of the renal artery stenosis, the more obvious the improvement of the renal function after the operation. Key words: Renal artery stenosis; Percutaneous renal artery stenting; Renal dynamic imaging; Single kidney glomerular filtration rate