Abstract
Objective: To study the changes of macular retinal thickness in children with moderate and low myopia by frequency domain OCT. Methods: 108 school-age children aged 7-12 years were selected and enrolled into the group. Among them, 58 cases (116 eyes) with simple moderate and low myopia in the myopia group and 50 cases (100 eyes) with straight eyes in the emmetropia group. The retinal thickness in different parts of macular area was compared between the two groups, and the correlation between retinal thickness in different parts of macular area and diopter and axial length was analyzed by Pearson correlation analysis. Results: The length of eye axis in moderate and low myopia group was longer than that in emmetropia group, and the difference was statistically significant (P < 0.05). There was no significant difference in CMT(Central Macular Thickness) and I-AMT(average macular thickness of inner circle) between the two groups (P > 0.05). The AMT(Average Macular Thickness) and O-AMT(average macular thickness of outer circle) in moderate and low myopia group were lower than those in emmetropia group, and the differences were all statistically significant (P < 0.05). The thickness of the retina below the macula and the nasal side was positively correlated with the refractive power in patients with moderate to low-grade myopia (r=0.201, 0.302, P＜0.05), and the thickness of the retina around the macula was negatively correlated with the refractive power (r=-0.326, P＜0.05). Conclusion: There is no significant difference in macular central retinal thickness between children with moderate and low myopia and normal children, and the thickness of paracentral retina tends to become thinner with the deepening of myopia.
Highlights
Refraction is a common eye disease in children, which is the main cause of poor eyesight in children
This study measured the length of eye axis and retinal thickness of macular area in 58 middle and low myopia and 50 low myopia, and analyzed the related factors of macular thickness change, which can promote the correct evaluation of myopia and the prevention of complications of ultra-high school-age children
Application mean of quantitative data ± The correlation between the equivalent spherical power and macular retinal thickness was analyzed by linear regression
Summary
Refraction is a common eye disease in children, which is the main cause of poor eyesight in children. Myopia has many degrees of retinal changes [1], including thinning of nerve fiber layer, leopard-print fundus, lacquered crack, myopic atrophy arc, neovascularization, etc. Such fundus changes are more likely to cause corresponding complications, which is the main pathological change of blindness in myopia patients. Study [4] found that the lengthening of eye axis increased the risk of pathological changes of retina. This study measured the length of eye axis and retinal thickness of macular area in 58 middle and low myopia and 50 low myopia, and analyzed the related factors of macular thickness change, which can promote the correct evaluation of myopia and the prevention of complications of ultra-high school-age children
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
