Abstract
This study investigated the effect of aging on spatial cognition performance and regional brain activation. Eight right-handed male college students in their twenties (mean age 21.5 years) and six right-handed male adults in their forties (mean age 45.7 years) who were graduated from college participated in the study. A spatial task was presented while brain images were acquired by a 3T functional Magnetic Resonance Imaging (fMRI) system. Compared to the 40s the 20s showed higher spatial performance. Increased brain activations were observed in the parietal and superior frontal lobes at 20s compared to 40s. There was more activation observed in the middle frontal and right inferior frontal lobes at 40s compared to 20s.
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