Abstract
Objective To analyze the clinical application value of platelet parameter changes before and after surgery in patients with subarachnoid hemorrhage in our hospital, and to provide basis for clinical condition observation. Methods A total of 354 patients with subarachnoid hemorrhage who were hospitalized in our hospital from January 2017 to July 2021 were selected, and compared with 217 healthy individuals during the same period. The 4 parameters in platelet venous blood before and after surgery were analyzed: platelet count (Plt), mean platelet volume (MPV), platelet volume (PCT), and platelet distribution density (PDW). Results Before operation: Platelet count (PLT) decreased compared with the normal control group (p<0.01), MPV and PDW were increased compared with the normal control group (p<0.01); PLT increased after operation (p<0.01), but higher than that of the normal control group. Conclusions Early surgical treatment of aneurysmal subarachnoid hemorrhage can seal the ruptured blood vessel, reduce the exposure of endothelial cells, inhibit platelet activation, and reduce the formation of microthrombi.
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