Abstract

The effect of nerve crush on the activity of nucleoside di‐and triphosphatases was studied in the hypoglossal nucleus of the albino rabbit with histochemical methods. Activity of nucleoside phosphatases was found in microglial cells. Golgi apparatus of the neurons and vascular walls. During nerve regeneration an increase in enzyme activity was observed in the microglial cells as well as an increase in the number of microglial cells. The Golgi apparatus of the regenerating neurons showed an initial decrease followed by increase in nucleoside phosphatase activity. After the first week an increase in capillarization and capillary enzyme activity could be demonstrated. The findings are discussed and an increased participation in uptake and transport during nerve regeneration is suggested for the cellular structures demonstrating nucleoside phosphatases.

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