Abstract
SummaryChanges in specific gravity of different areas of rabbit brain have been studied after exposure to 10 krads of x-rays to the head only. A triphasic change in brain specific gravity was found, i.e. a decrease from 0 to 1·5 hours after irradiation, followed by a short-lived rise to approximately pre-irradiation values at two hours after irradiation, and then a developing second decrease to 6 hours after irradiation. The initial decrease and short-lived increase in brain specific gravity appear to be due primarily to disturbances in circulatory relationships of the central nervous system, whereas the second decrease is due to a developing defect in brain permeability, as indicated by increased protein levels in the aqueous humour and cerebrospinal fluid, and by a developing brain oedema.
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Schedule a callMore From: International journal of radiation biology and related studies in physics, chemistry, and medicine
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