Abstract

BackgroundDifferent definitions have been proposed to categorize hypertension. We aimed to investigate the difference in prevalence of measures associated with hypertension according to the American College of Cardiology/American Heart Association (ACC/AHA) criteria versus Joint National Committee 7 (JNC7) criteria.MethodsWe analyzed the data of 10,000 participants of Yazd Health Study (YaHS) aged 20–69 years. Blood pressure was measured three times with standard protocol defined by ACC/AHA. Prevalence of high blood pressure measure was compared in both definitions and absolute differences reported.ResultsThe prevalence of high blood pressure in our measurement was 61.0% according to ACC/AHA, and 28.9% according to JNC 7. The prevalence of self-reported hypertension was 18.6%. Age and sex standardized prevalence rates of high blood pressure measure indicates a 2.4-fold increase in the prevalence rate (30.1% absolute difference) by the ACC/AHA guideline. While the prevalence increased in all age groups, the age group of 20–29 showed the highest relative increase by 3.6 times (10.6% vs. 38.1%). High blood pressure measure among people with diabetes increased from 45.8 to 75.3% with the ACC/AHA guideline. Of the people who had no past history of diagnosed hypertension (n = 7887), 55.1 and 22.7% had high blood pressure measure by ACC/AHA and JNC-7 guidelines, respectively. From JNC7 to ACC/AHA, the overall difference in unawareness about HTN increased by 32.4%.ConclusionPrevalence of hypertension associated measures increased over two folds by using the ACC/AHA criteria compared to JNC 7. Also, change in the criteria, reduces awareness of the disease and increases uncontrolled hypertension respectively. More research is needed to determine if the new definitions can affect management of hypertension in societies. Considering local priorities and implication of cost effective may improve implementation of new definitions for hypertension in different countries.

Highlights

  • Different definitions have been proposed to categorize hypertension

  • More research is needed to determine if the new definitions can affect management of hypertension in societies

  • The crude prevalence of high blood pressure associated with HTN according to JNC 7 guideline was 28.9% (CI 95%: 27.9–29.7), and according to the American College of Cardiology/American Heart Association (ACC/American Heart Association (AHA)) 2017 was 61.0%; an absolute increase of 32.1%

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Summary

Introduction

Different definitions have been proposed to categorize hypertension. We aimed to investigate the difference in prevalence of measures associated with hypertension according to the American College of Cardiology/American Heart Association (ACC/AHA) criteria versus Joint National Committee 7 (JNC7) criteria. Hypertension (HTN) is a global public health crisis; it is the most important risk factor for people with cardiovascular disease, which is one of the main causes of death and life lost in the world [1]. The prevalence of HTN was reported 20–50% across different world regions due to its differences in environmental and genetic factors and changes in the study protocol [2]. Blood pressure over 120/80 mmHg is linearly associated with the risk of cardiovascular disease, with an increase of 20 mmHg in systolic blood pressure and 10 mmHg in diastolic blood pressure, increase doubled the risk [8]

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