Abstract
Experiments were performed on six female and 36 male adult Wistar rats to compare the influences of dissociated cells obtained from different embryonic CNS rudiments on the growth of regenerating nerve fibers in damaged recipient nerves. Sciatic nerves were damaged by application of a ligature, after which some animals received injections of suspensions of cells into the proximal nerve segment, using cells obtained by dissociation of spinal cord or anterior cerebral vesicle fragments from rats at 15 days of development. These experiments showed that injection of dissociated cells from embryonic spinal cord rudiments but not neocortex rudiments into the damaged nerve led to increases in number of myelinated nerve cells in recipients at 60 days.
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