Changes In the Morphology of Neurons of The Parietal Cortex and Hippocampus of Rats in The Dynamics of Step Subtotal Cerebral Ischemia

Abstract

The study of the brain in norm and pathology is an urgent and promising direction of modern science and, in this regard, a frequent topic of dissertation research. Cerebral ischemia leads to a number of general and local metabolic and functional disorders, the pathogenesis of which is complex, multifaceted and largely. The aim was to change the morphology of neurons in the parietal cortex and hippocampus of rats in the dynamics of stepwise subtotal cerebral ischemia. With stepwise bilateral ligation of both common carotid arteries with an interval of 7 days, negative changes were least pronounced, especially in the hippocampus. The longer the interval between dressings, the more effectively neurons adapt to lack of oxygen, which makes it possible to further study in more detail the dynamics of the mechanisms of damage development and adaptive changes in the brain.