Abstract
A comprehensive multicomponent method was used for the determination of organochlorine contaminants in human milk. The investigation of pooled samples from 1972, 1976, 1980 and 1984–1985 indicated a decrease of the levels not only of pesticides and polychlorinated biphenyls (PCBs) but also of polychlorinated dibenzo- p -dioxins (PCDDs) and dibenzofurans (PCDFs) and of pentachlorophenol. The concentrations of PCDDs and PCDFs decreased markedly in one of two mothers studied during consecutive nursing periods. A positive correlation of the concentrations of certain PCDDs and PCDFs and of pentachlorophenol to the fat content of the milk is demonstrated.
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