Abstract
Chalkbrood is a type of common fungal disease that affects colony health, productivity, and pollination of honey bees. In this study, resistant and susceptible larvae towards chalkbrood were initially determined by using SNP C2587245T. We compared the transcriptome of the resistant and susceptible individuals challenged with Ascosphaera apis and found that 172 and 207 genes were specially and differentially expressed in the midguts and hemolymph of the resistant larvae infected with A. apis, respectively. Besides, the immune response of honey bees infected with A. apis was investigated. Most interestingly, it was found that the antimicrobial peptide defensin 1 was significantly and exclusively upregulated in the hemolymph of the resistant individuals infected with A. apis. This comprehensive transcriptome analysis substantially helped enhance our understanding of the mechanisms of chalkbrood resistance and the corresponding gene expression during infection with A. apis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
