Changes in the gas composition of umbilical cord blood of newborns after cesarean section using various protocols of general anesthesia in dogs

Abstract

Cesarean section, being one of the most common operations in veterinary surgery, requires a special anesthetic protocol that provides adequate anesthesia for the mother and has minimal effect on puppies. The aim of the study was to evaluate the effect of various non-inhalation and inhaled anesthetics on newborn puppies during cesarean section, based on the analysis of cord blood gases. 3 groups of experimental animals were formed, which used one of the studied anesthetic protocols. In the first experimental group, propofol at a dose of 4-6 mg/kg was used to maintain general anesthesia. Inhaled halogen-containing anesthetics were used in the second and third experimental groups. Isoflurane 0.5 – 2.0 vol% was used in the second group, and sevoflurane 1.0 – 2.0 vol% was used in the third group. When using all the studied anesthetics, an acidbase imbalance in the form of moderate acidosis was detected in the puppies after delivery, however, acidosis was less pronounced in the groups where halogen-containing anesthetics were used. The use of inhaled halogen-containing anesthetics had a lesser effect on puppies compared to non-inhalation ones. There were no significant differences in the effect of isoflurane and sevoflurane from inhaled anesthetics.