Changes in the electrobiological activity of the brain in full-term newborns with hypoxic-ischemic encephalopathy

Abstract

Early diagnosis of hypoxyc encephalopathy contributes to the timely correction of neurofunctional disorders, which reduces mortality and the severity of acute and distant neurological complications of cerebral injurie. The importance of early detection of cerebral disorders in newborns has become especially relevant with the introduction of therapeutic hypothermia in full-term infants with hypoxic encephalopathy. It has been established that with the early onset of therapeutic hypothermia, full-term neurological prognosis in the long-term period, including motor, is observed in full-term newborns. The correspondence between structural disorders and neurophysiological changes in the brain at different age periods is proved. Among the methods for the early diagnosis of cerebral injuries in newborns, the electroencephalogram is one of the leading places. The correspondence between structural disorders and neurophysiological changes in the brain at different age periods is proved. Such characteristics of the electroencephalography method as non-invasiveness, high sensitivity in assessing neurobiological activity, safety, delicacy in maintaining the stability of a critical patient, allows electroencephalography in newborns from the first hours of life. The relevance of the review is associated not only with the scattered information about changes in the electrical activity of the brain in children with hypoxic-ischemic encephalopathy in the neo. Describes the main poor prognostic EEG patterns in the form of a suppression rate (decrease in the amplitude with the maximum manifestation of the oppression of the electrobiological activity in the form of a pattern burst suppression), slowing of the basic rhythm, rarely revealed epileptic, epileptiform activity, focal sharp activity. Such characteristics of the electroencephalography method as non-invasiveness, high sensitivity in assessing neurobiological activity, safety, delicacy in maintaining the stability of a critical patient, allows electroencephalography in newborns from the first hours of life. The relevance of the review is associated not only with the scattered information about changes in the electrical activity of the brain in children with hypoxic-ischemic natal period, but also with the peculiarity of brain electrogenesis during the neonatal period.