Abstract
BackgroundGastrooesophageal reflux disease (GERD) is a spectrum of symptoms arising from the laxity of the cardio-oesophageal junction. Anti-reflux surgery is reserved for patients with refractory GERD. Anterior partial fundoplication (Dor) is a regularly performed anti-reflux surgery in Malaysia. We intend to determine the improvement in disease-specific quality of life in our patients after surgery. MethodsA multicentre cross-sectional study was conducted to assess patients’ improvement in disease-specific quality of life after Dor fundoplication. Ethics approval was obtained from our institutional review board. Patients between the ages of 18 and 65 years who underwent Dor fundoplication within the past five years were assessed using the GERD HRQL as well as the VISICK score via telephone interview. We excluded cases of revision surgery. ResultsOut of 129 patients screened, 55 patients were included. We found a significant improvement in patients’ GERD HRQL score with the pre-operative mean score of 28.3 ± 9.39 and 6.55 ± 8.52 post-operatively, p < 0.01.50.9% of patients reported a VISICK score of 1. However, we noticed a deterioration in the GERD HRQL and VISICK score in patients followed up four years after surgery. This consisted of 25.5% of total patients. ConclusionDor Fundoplication improves the overall disease-specific quality of life in patients with refractory GERD in the short term period. Recurrence of symptoms causing a deterioration in the quality of life is seen in patients followed up beyond four years of index surgery.
Highlights
The passage of stomach contents into the oesophagus is a physiological process, termed gastrooesophageal reflux
We noticed a deterioration in the Gastrooesophageal reflux disease (GERD) Health-Related QoL (HRQL) and VISICK score in patients followed up four years after surgery
The prevalence of GERD in the Asian population was studied in two separate studies in Singapore, and it showed a four-fold increase, from 1.6% in 1994 to 10.6% in 2001 [3], [4]
Summary
The passage of stomach contents into the oesophagus is a physiological process, termed gastrooesophageal reflux. Methods: A multicentre cross-sectional study was conducted to assess patients’ improvement in disease-specific quality of life after Dor fundoplication. Patients between the ages of 18 and 65 years who underwent Dor fundoplication within the past five years were assessed using the GERD HRQL as well as the VISICK score via telephone interview. We noticed a deterioration in the GERD HRQL and VISICK score in patients followed up four years after surgery. This consisted of 25.5% of total patients. Conclusion: Dor Fundoplication improves the overall disease-specific quality of life in patients with refractory GERD in the short term period. Recurrence of symptoms causing a deterioration in the quality of life is seen in patients followed up beyond four years of index surgery
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