Changes in the characteristics of the oral fluid in smokers of electronic cigarettes and tobacco heating systems

Abstract

Objective: to evaluate the effect of smoking electronic (SE) cigarettes and tobacco heating systems (THS) on the characteristics of changes in the characteristics of the oral fluid. Material and methods. The results of analysis of oral fluid samples of 150 persons were studied: smoking ES/THS — 50 people each in the group; control group — 50 clinically healthy non-users of ES/THS. Results. Patients in the THS group have a lower salivary secretion rate, a higher oral fluid viscosity at a more neutral salivary pH than control group (p=0.002); whereas patients of the ES group in comparison with the THS group are characterized by a higher saliva secretion rate, a lower viscosity index of the oral fluid at a neutral saliva pH level (p>0.05). Differences were observed in biochemical parameters of total protein concentration (p=0.001), oral fluid calcium concentration (p=0.005), malonic dialdehyde (p=0.007), alkaline phosphatase, and salivary catalase concentration (p=0.004 and p=0.006, respectively) between THS smokers and control group. Conclusion. Smoking THS to a greater extent in comparison with ES and especially with control group reduces the rate of salivation, increases the viscosity of the oral fluid; in this group of smokers, in comparison with ES smokers, a more neutral value of oral fluid acidity was revealed, the concentration of total protein, malonic dialdehyde, phosphates and calcium in saliva was increased with a decrease in alkaline phosphatase and catalase concentrations.