Abstract
The effects of immobilization (1 h/day) of female rats from days 15 to 18 of pregnancy on the secretion of sex steroid hormones depending on the stage of the estrous cycle, functional activity of the hypophyseal-adrenocortical system (HAS), and its sensitivity to regulatory signals were studied in their female offspring at different stages of ontogeny. Prenatal stress was found to lead to significant impairments to the activity of the sexual system depending on the animals’ age. Older females showed a significant decrease in HAS sensitivity to feedback signals. These data provide evidence that maternal stress has a modifying effect on changes in the reproductive functions of female rats with age and on the significant decrease in the efficacy of the feedback functions of the HAS.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
