Abstract

THAT tissues and organisms differ widely among themselves in radiosensitivity has long been recognized, but comparatively little, it seems, is known of how any one tissue or organism may change in susceptibility to radiation with respect to time or age. While studying the killing effects of x-rays on Drosophila melanogaster eggs, certain irregularities in results were obtained. An investigation showed these to be due mainly to the age of the material used. The determination of the significance of the age factor served not only as a foundation for other work in which Drosophila eggs were to be used as test material, but also to show how an organism may vary in susceptibility to radiation during development. Since certain stages in the early development of this form are distinct and easily recognizable, it is possible to associate the changes in radiosensitivity with the stages in development and thus ascertain whether or not the nature of the activity going on within the organism is important in determinin...

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