Changes in submaxillary glands after isoproterenol injection into intact and depancreatized mice

Abstract

Using antiserum against smooth muscle myosin of human uterus the distribution of myosin was investigated in primary cell culture of human aortic intima. It was discovered that during the first 5 days of cultivation, 74.5% of cells manifested homogenous distribution of myosin. Single cells contained myosin in the form of continuous fibrils and 25% of cells were not stained by antiserum. In the next days of cultivation the cells experienced modulation and on the 14th day less than 6% of cells were stained homogeneously, while 58.5% of cells were not stained by antiserum. It is assumed that part of human aortic intima cells might be phenotypically modulated.