Abstract

The lipolytic activity of adipose tissue (LAAT), the concentration of nonesterified fatty acids (NEFA) in the blood and adipose tissue, and the concentrations of ketone bodies and β-lipoproteins in the blood of dogs were determined after lethal exsanguination and in the post-resuscitation period. During agony activation of lipolysis was found in the adipose tissue, the levels of NEFA and β-lipoproteins were lowered, and the concentration of ketone bodies in the blood was increased. At the end of the third minute of clinical death inhibition of lipolysis developed and the NEFA concentration in the adipose tissue increased. The blood levels of NEFA and β-lipoproteins fell 1 h after resuscitation, whereas the level of ketone bodies rose; these changes were accompanied by some decrease in LAAT. In the late postresuscitation period (1st, 3rd, and 7th days) LAAT and the blood levels of NEFA, ketone bodies, and β-lipoproteins all increased. The NEFA concentration in the adipose tissue was low in the postresuscitation period.

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