Abstract
In a study of 18 patients on haemodialysis, erythrocyte δ-aminolaevulinic acid dehydratase (ALAD), serum aluminium, blood zinc and blood lead concentrations were increased significantly following haemodialysis. The increase in erythrocyte ALAD activity was found to be significantly linearly correlated with the increase in blood zinc concentrations. In comparison with control subjects, the patients had significantly lower activities of ALAD and significantly increased serum aluminium concentrations. When zinc and lead concentrations were corrected for packed cell volume they were found to be significantly higher in the patient group than in the control group.
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